Br J Obstet Gynaecol. 1975 May;82(5):424-5.
Topical oestrogen therapy for labial adhesions in children.
Aribarg A.
Labial adhesions separated spontaneously after one month of the topical oestrogen therapy in 22 (88 per cent) out of 25 children. This treatment was safe, painless, without significant complications and of lasting value. PIP: 25 children, 2-24 months old, who had severe labial adhesions involving the entire length of the labia minora were treated with .01% dienestrol cream applied locally on a daily basis. Adhesions separated after treatment in 22 children; duration of treatment was 1 week in 8 patients, 2 weeks in 10 patients, 3 weeks in 3 patients, and 4 weeks in 1 patient. Slight vulval pigmentation occurred in almost all patients but disappeared after medication was stopped. 1 patient had erythema of the vulva. Recurrence of adhesions was infrequent.
