The first signs of increased androgen levels (hyperandrogenism) are hirsutism and acne. The sensitivities of individuals to hormone levels vary considerably. When there are high androgen levels, other signs of virilisation may be found including muscle enlargement, deepening of the voice, reduction or absence of periods, reduced breast size and enlargement of the clitoris. About 50% of women with hirsutism have normal hormone levels although there is likely to be increased activity of the skin enzyme '5 alpha- reductase', which raises local androgen levels. Eventually there may be male pattern balding.


women's health


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