Intrauterine insemination and Infertility Treatment

This paper presents the analysis of 901 cycles of intrauterine artificial insemination with the husband's spermatozoa (AIHIU) in 274 couples who obtained 80 pregnancies. The cumulative pregnancy rate after three cycles of AIHIU was 22% and reached 39% after six cycles. Univariate analysis disclosed two factors of poor prognosis: duration of infertility > 3 years (P = 0.01) and husband's age (P = 0.03). Multivariate analysis revealed that the most significant factor contributing to a decreased likelihood of pregnancy was the age of the husband (P = 0.01), then duration of infertility and dysovulation. The wife's age > or = 35 years did not appear to be of poor prognostic value when taking into consideration the three other factors.

Please click on the required question.

• 1 What are the objectives of infertility treatment?
• 2 Why have I been advised to take folic acid as part of my infertility treatment?
• 3  Although my ovaries have eggs in them, my tests show that I am not releasing them (anovulation) and this is causing infertility. How can this be treated?
• 4 If I take drugs to induce ovulation (ovulation induction) for my infertility, are there any risks?
• 5 How is ovulation induction treatment for infertility monitored?
• 6 How does clomiphene citrate work for infertility?
• 7  How effective is clomiphene in the treatment of infertility?
• 8 Could I experience any problems whilst taking clomiphene?
• 9 Is there any advantage in having an injection of HCG to ensure ovulation?
• 10 How does tamoxifen work?
• 11 How can hyperprolactinaemia be treated?
• 12 How does metformin work?
• 12A How does letrozole work for infertility?
• 13 How do gonadotrophins work?
• 14 What are the risks for me if I receive gonadotrophin therapy?
• 15 What are recombinant gonadotrophins?
• 16  What is ovarian hyperstimulation syndrome (OHSS)
• 17 How is ovarian hyperstimulation syndrome treated?
• 18 How does electrocautery (ovarian drilling) work for infertility associated with polycystic ovary syndrome (PCOS)
• 19 I have been found to have endometriosis. How should this be treated to improve my chance of conceiving?
• 20 Tests have shown that I have problems with my Fallopian tubes. What can be done about this?
• 21 I have fibroids. How should these be treated to improve my fertility?
• 22 My post-coital test has shown that my mucus is stopping the sperm from swimming (mucus hostility). What can be done?
• 23 When can intrauterine insemination (IUI) improve our chance of achieving a pregnancy?
• 24 What is in vitro fertilisation (IVF) and embryo transfer (ET)
• 24A IVF single or double embryo transfer?
• 25 What is intracytoplasmic sperm injection (ICSI)
• 26 How do tubal surgery and IVF compare?
• 27 What are egg donation and egg sharing?
• 28 What is selective embryo transfer?
• 29 Investigations have shown no obvious cause for our difficulty achieving a pregnancy. Are there any treatments for our unexplained infertility?
• 30 We have tried a variety of treatments but we still have not achieved a pregnancy. Why should this be?
• 31  We are finding the investigation and treatment of our fertility problems to be ever more stressful. Can stress be a cause of infertility?
• 32 How can we determine which fertility unit is likely to be the best for us?
• 33 Where can I obtain more information?
• 34 Support Groups.
  

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This is the personal website of David A Viniker MD FRCOG, Consultant Obstetrician and Gynaecologist at Whipps Cross University Hospital, London - Specialist Interests - Reproductive Medicine including Infertility, PCOS, PMS, Menopause and HRT.

I do hope that you find the answers to your women's health questions in the patient information and medical advice provided.