The London Women's Clinic, Canada.
Objectives:
To provide an assessment of pregnancy and live birth probabilities for women presenting for in vitro fertilisation treatment for the first time, when committed in advance to have up to three cycles of treatment in one year.
Design:
Up to three cycles of in vitro fertilisation within one year, committed in advance.
Setting:
A tertiary referral centre for assisted reproduction. PARTICIPANTS: Two hundred and thirty-two women, undergoing a total of 536 cycles of in vitro fertilisation or intracytoplasmic sperm injection between August 1993 and December 1995.
Methods:
Analysis of cumulative clinical pregnancy and live birth rates for women having IVF treatment for the first time and undertaking a three-cycle package, using the life-table approach.
Settings, Design and Main Outcome Measures:
Cumulative clinical pregnancy and live birth rates.
Results:
The cumulative probabilities of clinical pregnancy and live birth after two cycles of treatment were 38.2% and 33.2%, respectively, compared with 54.2% and 48.2%, respectively, after three cycles of treatment. Cumulative clinical pregnancy and live birth rates after three cycles of treatment for women up to the age of 40 years were 57.8% and 51.3%, respectively. Cumulative clinical pregnancy and live birth rates declined with increasing age (P = 0.02 and P= 0.01, respectively).
Conclusion:
The three-cycle package encourages couples to have multiple treatment cycles, thereby improving their ultimate chances of a live birth. The cumulative clinical pregnancy and live birth rates after such a package provide a more realistic assessment of overall and age-specific success rates after multiple treatment cycles.
Please click on the required question.
- Q 11. 1 How successful is infertility treatment?
- Q 11. 2 How can we compare infertility treatments?
- Q 11. 3 How can we compare outcomes between different fertility units?
- Q 11. 4 Are treatments for infertility improving?
- Q 11. 5 Is there an increased chance of miscarriage following infertility treatment?
- Q 11. 6 Is there an increased chance of ectopic pregnancy following infertility treatment?
- Q 11. 7 What is a heterotopic pregnancy?
- Q 11. 8 What problems can occur with multiple pregnancy?
- Q 11. 9 What is selective termination of pregnancy?
- Q 11. 10 How can the pregnancy risks following infertility treatment be reduced?
- Q 11. 11 We have had infertility treatment which has been successful. How will our pregnancy be cared for?
- Q 11. 12 If we have infertility treatment, will our baby be healthy?
- Q 11. 13 What are the psychological effects of infertility? information?
- Q 11. 14 Where can I obtain more information?
- Q 11. 15 Support Groups.
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This is the personal website of David A Viniker MD FRCOG, Consultant Obstetrician and Gynaecologist at Whipps Cross University Hospital, London - Specialist Interests - Reproductive Medicine including Infertility, PCOS, PMS, Menopause and HRT.
I do hope that you find the answers to your women's health questions in the patient information and medical advice provided.
