Hormone contraceptives have three potential modes of action:

  • They cause the cervical mucus to be thick and therefore impenetrable to sperm.
  • The lining of the uterus (endometrium) remains thin and not capable of allowing succ the combined oral contraceptive pill, follicular development and ovulation (egg ressful implantation of an embryo.
  • With the combined oral contraceptive pill, follicular development and ovulation (egg release) are suppressed.

The normal menstrual cycle involves a cycle of hormone stimulation and suppression (menstrual cycles). The pituitary gonadotrophic hormones (FSH and LH) stimulate follicular development and ovulation and the oestrogen from the follicles prevents pituitary hormone levels from rising (negative feedback). The oestrogen in the combined oral contraceptive pill suppresses FSH and LH so that follicular development and oocyte release are infrequent at most.

Progesterone and progestogens result in the cervical mucus being thick. In the normal menstrual cycle, progesterone levels rise only after ovulation. Progestogen is present in each of the hormone contraceptives and this keeps the mucus thick even at the time of ovulation. The endometrium in a normal cycle becomes thickened before ovulation (proliferative phase) in preparation for a possible embryo to become implanted. Progestogen, when present throughout the cycle, prevents adequate proliferation for implantation.


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This is the personal website of David A Viniker MD FRCOG, Consultant Obstetrician and Gynaecologist at Whipps Cross University Hospital, London - Specialist Interests - Reproductive Medicine including Infertility, PCOS, PMS, Menopause and HRT.

I do hope that you find the answers to your women's health questions in the patient information and medical advice provided.





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