Rev Assoc Med Bras. 2006 Jan-Feb;52(1):32-6.
Weight variation in users of the levonorgestrel-releasing intrauterine system, of the copper IUD and of medroxyprogesterone acetate in Brazil
Yela DA, Monteiro IM, Bahamondes LG, Del Castillo S, Bahamondes MV, Fernandes A.
Departamento de Obstetr?ia e Ginecologia, Faculdade de Medicina, Universidade Estadual de Campinas (UNICAMP), Campinas, Brazil. yeladaniela@hotmail.com
Background:
Assess weight variations in Brazilian users of the 20 microg/day levonorgestrel-releasing intrauterine system (LNG-IUS, Mirena) for comparison with a cohort of users of the TCu 380A intrauterine device (IUD) and a cohort of users of the injectable contraceptive, depot-medroxyprogesterone acetate (DMPA) over a period of five years.
Methods:
A total of 163 users of the LNG-IUS, who had the device inserted in 1998, were admitted to the study. At the time of enrollment, each woman was matched by weight (+/- 1 kg) and age (+/- 1 year) to a woman using a TCu 380A IUD and to another woman using DMPA. All women were followed up for a period of five years. Each year weight was measured and the body mass index (BMI, kg/m2) was calculated.
Results:
Age of the LNG-IUS users was 27.0 +/- 6.7 years (mean +/- SD), while age of the copper IUD users was 28.0 +/- 6.6 years and that of DMPA users was 26.9 +/- 6.5 years. Weight recorded at the onset of the study was 62.9 +/- 0.8 kg, 62.8 +/- 0.8 kg, and 62.5 +/- 0.9 kg (Mean +/- SD) for users of the LNG-IUS, the copper IUD, and DMPA, respectively. The BMI of women was initially 25.0 (+/- 0.3), 26.4 (+/- 0.3), and 25.5 (+/- 0.4), (Mean +/- SD), for users of the LNG-IUS, copper IUD, and DMPA, respectively. Weight increases of 3.1 kg, 4.9 kg and 8.2 kg were observed at the end of the fifth year among users of the LNG-IUS, copper IUD, and DMPA, respectively (p = 0.009). Increase of the BMI was also observed among all groups (final BMI was 26.3 +/- 0.7, 28.5 +/- 0.8 and 28.7 +/- 1.3 for users of the LNG-IUS, copper IUD and DMPA, respectively). Multivariate analysis showed that there was a significant association between weight increase and length of use of the contraceptive method and of the DMPA.
Conclusion:
The use of a LNG-IUS during five years caused no significant weight increase and the difference in weight was of the same magnitude as that of copper IUD users.
Please click on the required question.
- 1 What types of hormone contraceptives are available?
- 2 How effective are hormonal contraceptives?
- 3 How do hormone contraceptives work?
Progestogen-only pills
- 4 What is a progestogen-only pill?
- 5 How do progestogen-only pills provide contraception?
- 6 How does the progestogen-only pill compare to the combined oral contraceptive pill?
- 7 When are POPs recommended in preference to COPs?
- 8 How effective are progestogen-only pills?
- 9 When should POPs be started and how quickly are they are effective?
- 10 When should progestogen-only pills be taken?
- 11 What should be done if a POP is missed?
- 12 What will happen to my periods whilst I am taking progestogen-only pills?
- 13 What should be done if my periods stop when I am taking the progestogen-only pill?
- 14 What should be done if vomiting occurs?
- 15 Should additional precautions be used during a course of antibiotics?
- 16 Can POPs cause ovarian cysts?
- 17 Should the POP be discontinued before I have an operation?
Long-acting hormonal contraception.?
- 18 What are long-acting hormonal contraceptives?
- 19 Depo-Provera What is Depo-Provera?
- 20 What are the advantages of Depo-Provera?
- 21 I have recently had a Depo-Provera injection and now I need to have an operation. Will the operation be delayed?
- 22 What are the disadvantages of Depo-Provera?
- 23 Will my fertility return three months after my last Depo-Provera injection?
- 24 Do long-acting hormonal contraceptives increase the risk of cancer?
- 25 What are contraceptive implants?
Levonorgestrel Intrauterine System - LNG-IUS - Mirena
- 26 Mirena: What is the Levonorgestrel Intrauterine System (LNG-IUS)
- 27 How does the Mirena work?
- 28 How effective is the Mirena as a method of family planning?
- 29 How would a Mirena effect my long-term fertility?
- 30 How long has the Mirena been in use?
- 31 How is the Mirena introduced into the womb?
- 32 How quickly will a Mirena work?
- 33 What problems can occur with the Mirena?
- 34 How frequently should my Mirena be changed?
- 35 What will happen to my periods after a Mirena is introduced?
- 36 What value is Mirena in the management of period problems?
- 37 What value is Mirena for premenstrual syndrome?
- 38 What value is Mirena in Hormone Replacement Therapy?
- 39 Family Planning Support Groups.
- 40 Support Groups.














