What is the relationship between the combined oral contraceptive pill and cancer of the cervix?


Sexual activity and number of partners are the factors that have large impacts on the incidence of pre-malignant and malignant conditions of the cervix (neck of the womb - Q32.16). The sheath (condom) provides mechanical protection not only against pregnancy but also against sexually transmitted disease. It prevents transmission of the human papilloma virus believed to be responsible for cervical cancer. It may be that the early studies suggesting that the combined oral contraceptive pill increased the risk were only reflecting the prevention of transmission of the virus with the barrier method.

There has been a suggestion that the combined oral contraceptive pill may increase the chance of pre-malignant conditions of the cervix developing in women at risk but this remains an area of debate requiring more data. There is no reason to stop the combined oral contraceptive pill if you have been found to have an abnormal smear test provided appropriate investigations and treatment are undertaken (Pap Test).


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