Articles for March 2016

New method reveals high similarity between gorilla and human Y chromosome

New technique reveals high similarity between gorilla and human Y chromosome

For full capability, it is needed to make it possible for JavaScript. Here are directions the best ways to enable JavaScript in your web browser. We make use of cookies to personalize your surfing experience. By visiting our website, you agree to their use. Learn more. A new, less expensive, and quicker approach now has been developed and made use of to figure out the DNA sequence of the male-specific Y chromosome in the gorilla. The technique will enable much better access to genetic info of the Y chromosome of any species and thus can be made use of to study male infertility conditions and male-specific mutations. It also can help in preservation genetics efforts by helping to trace paternity and to track how males move within and in between populations in endangered species, like gorillas. A paper explaining the technique and the discovery resulting from its usage in comparing the series of the gorilla Y chromosome to the series of the human and chimpanzee Y chromosomes is released in the Advance Online edition of the journal Genome Research study. “Remarkably, we discovered that in numerous methods the gorilla Y chromosome is more similar to the human Y chromosome than either is to the chimpanzee Y chromosome,” stated Kateryna Makova, the …
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New ‘gene modifying’ of human embryos approved for research study in UK

The scientists plan to make use of the new strategy – called CRISPR-Cas9 – to find out which genes assist human embryos establish successfully. They want to begin the research study in the next few months, subject to it getting ethical approval. The results of the job – which will take a look at the very first 7 days of a fed egg’s development (from a single cell approximately 250 cells) – might give new insights into why miscarriages happen and improve understanding of in vitro fertilization (IVF) success rates. The Human Fertilisation and Embryology Authority (HFEA) licence does not enable the scientists to grow the embryos in the lab beyond 14 days after fertilization. The embryos will be contributed by clients undergoing IVF treatment who have offered their notified consent to enable use of surplus embryos for research study. The licence restricts using donated embryos for research study purposes only – it does not allow them to be moved to a woman or made use of in treatment. The Crick research study will be led by Dr. Kathy Niakan, whose research concentrates on comprehending the molecular and genetic mechanisms that manage cell modifications in early human advancement. Making use of CRISPR-Cas9 to edit the genome of a fertilized human egg, th …
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‘IVF chip’ helps capture images of sperm fusing with egg

Now, new methods – including an “IVF chip” – provided recently at the Biophysical Society’s 60th yearly meeting in Los Angeles, CA, promise to reveal brand-new insights into how a single sperm cell merges with an egg cell. The scientists hope the new strategies will assist us better understand the causes of infertility and enhance treatments. At the meeting, Benjamin Ravaux, a physics college student at the Ecole Normale Supérieure de Paris in France, described how, using the “entirely new method,” he and his colleagues caught high-resolution pictures of the events that unfold at the membrane of the egg cell during mammalian fertilization. Ravaux says the “IVF chip” is a “unique tool to observe the waterfall of molecular and membrane occasions occurring throughout the fertilization process,” under conditions that mimic what happens in nature. The concept and design of the gadget are the product of competence in biophysics and fertilization and assisted reproduction innovations (ART) – consisting of in vitro fertilization (IVF). At the heart of the new method is an “IVF chip” – a microfluidic device made from an electronic chip comprising numerous layers of silicon polymer sealed on a glass sli …
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Asthma connected to an increased time to pregnancy

Asthma has been related to a prolonged time to pregnancy and a reduced birth rate in a new medical observation research study. Released in the European Breathing Journal, the research contributes to previous researches that have determined a link in between asthma and fertility. The proof up until now has been contrasting and a number of the research studies have either depend on data from surveys or small sample sizes. The current study examined 245 ladies with unexplained fertility issues aged between 23 and 45 years. They went through asthma and allergy screening and questionnaires during their fertility treatment. 96 females in the research had either an existing medical professional’s diagnosis of asthma or were identified with asthma when they got in the research. The researchers kept track of the females during their fertility treatment for a minimum of 12 months, till they had a successful pregnancy, stopped treatment or the observation ended. The results found that the average overall time to pregnancy was 32.2 months in non-asthmatic females and 55.6 months in those with asthma. Women with asthma likewise had less effective conceptions: 39.6 % achieved pregnancy in the asthmatic women compared to 60.4 % in the ladies without …
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Zebrafish embryos exposed to atrazine pass on health issue to their young

Atrazine exposure during embryonic advancement could cause later reproductive issues for female zebrafish, as well as physical deformations in their offspring, according to new research study from Purdue University. “This technique to reveal the later-in-life effects is unique due to the fact that this is the first study of the offspring of female fish that were exposed to atrazine during their very first 72 hours of life,” said Jennifer Freeman, an associate professor of toxicology in the School of Health Sciences. “Other researches expose the parents when they are adults and then study the offspring. But by exposing throughout embryogenesis, we will have a much better concept of the overall impacts. For example, we discovered physical contortions in the offspring along with complications with breeding and increases in progesterone for the parents.” These findings are reported in Nature’s Scientific Reports, and the research study was supported by the National Institutes of Health and the National Institute of Environmental Health Sciences. Atrazine, an agricultural herbicide, is a thought endocrine-disrupting chemical. It is used to kill broadleaf and grassy weeds in crops, such as corn, especially in the Midwest, and it of …
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Diet and Weight Loss

Introduction to Dieting and Weight Loss

This webpage on diet and weight loss with its references is available.

There is a vast array of information on healthy eating and weight management.

The enormous number of promoted regimes makes it hard to find a suitable diet and stick to it.

For the last generation or two there has been a rapid increase in those who are overweight (BMI >25) and those who are obese (BMI>30).

The energy equation

  • Calories expended on exercise > calories in food = weight loss

  • Eat more calories than we Use = weight gain

All programs designed to achieve weight loss must utilise this e quation.

Complex factors affect how and why we eat and how efficiently we burn calories. These include:

  • hereditary factors
  • age
  • general health
  • emotional response to food

The pros and cons to every diet affect individuals differently.

  • Successful weight loss plans only work by changing the balance between calories in and calories out.
  • Increasing calories out is a key element and you need to increase your excercise.
  • You should aim to lose 400 – 800 g (1-2lb) each week.

Calorie Counting Diets

  • Controlling our intake by counting calories in everything we eat and drink is logical and scientific.
  • Many people find it difficult to keep counting the calories even when they have learned the calorie counts of their favourite foods and drinks.
  • You can find charts on caloriecountercharts.com and thecaloriecounter.com

 

Low-Carbohydrate Diets – Atkins Diet

At one time more than a million people in the UK were following low-carbohydrate diets particularly when this was popularised in the Atkins Diet but their popularity has waned.

Atkins Diet or just ‘Atkins’, is a well-known low-carbohydrate diet created by Dr.Robert Atkins from a diet he read in the Journal of the American Medical Association and utilized to resolve his own overweight condition. He later popularized the Atkins diet in a series of books, starting with Dr. Atkins’ Diet Revolution in 1972.

Various factors, however, led to its dwindling success and the company founded by Dr. Atkins in 1989, Atkins Nutritionals bankruptcy in  2005, two years after the death of Dr. Atkins.

Dr. Atkins rejected the conventional advice instead asserting that the increase in refined carbohydrates is responsible for the rise in metabolic disorders of the 20th century, and that the focus on the detrimental effects of dietary fat has actually contributed to the obesity problem by increasing the proportion of insulin-inducing foods in the diet.

The Atkins diet involves the restriction of carbohydrates in order to switch the body’s metabolism from burning glucose to burning stored body fat. Many incorrectly believed that the Atkins Diet promoted eating unlimited amounts of fatty meats and cheeses. This is a key point of clarification that Dr. Atkins addressed in the  revisions of his book. Although the Atkins Diet does not impose limits on certain foods, or caloric restriction in general, Dr. Atkins pointed out that this plan is “not a license to gorge.”

An attraction of these diets is that they offer an unlimited quantity of protein foods such as meat, fish and eggs together with unlimited fats including butter but virtually no carbohydrates such as cereals.

  • Proponents of the Atkins diet believe that these diets reduce digestible energy.
  • Opponents believe that the Atkins diet is self limiting because it is not palatable long-term.

The British Diabetic Association could not recommend this solution as it could have adverse effects on the kidneys and heart.

Research has confirmed quick short-term weight loss with the Atkins diet but the medium (six months) and long-term loss is no better than other diets.

Low-Fat Diets

Fat 9 calories per gram than either carbohydrate or protein – 4 calories each.

  • No more than 30% of dietary calories should come from fat – a low fat diet would reduce this to a maximum of 20%.
  • The fat in the diet should be monounsaturated or polyunsaturated as found in oily fish or olive oil.
  • Saturated fats, such as in fatty meat or full fat dairy products should be reduced as much as possible.

High-Fibre Diets

Fibre is essential for good health with a recommended minimum of 20-25g / day.

Filling up on high fibre foods can achieve satiation whilst reducing high calorie foods.

They take time to eat and release glucose slowly into the blood which makes you less likely to indulge in snacks.

Bran, wholegrain cereals, bread, pasta, brown rice and vegetables are rich in insoluble fibre and fruit, oats, beans and peas are sources of soluble fibres.

Initial side effects of high fibre diets are flatulence, stomach noises, bloating and sluggishness but these resolve with time. Fluids are to be encouraged to avoid these problems.

Glycemic Index (GI) Diets

GI diets revolve around the role of carbohydrates (sugar and starch foods) and in particular on the speed at which carbohydrates are digested into glucose and released into the circulation.

  • The concept originated in the care of diabetics where the objective is to prevent blood sugar levels rising too high. foods with low GI result in fewer peaks and troughs.
  • Diabetics are advised to include low GI foods with most meals.
  • The glycemic index is a classification of carbohydrates according to the speed they are digested.
  • Glucose is rapidly absorbed into the blood stream and has a GI rating of 100, spaghetti a GI o 41 and grapefruit 14.

The theory of low GI diets is that by using carbohydrates that have a low GI, hunger is reduced. Slimmer’s on low-GI diets have little high-sugar, high-fat snacks but eat low-fat-high fibre food.

  • These diets conform with current concepts of a “healthy diet”.
  • Low-GI carbohydrates (rating< 60) include most fruits and vegetables, wholemeal bread, porridge, rice, beans and peas.
  • High-GI foods which are to be kept to a minimum include white bread, white rice, sweet breakfast cereals, cakes and biscuits.
  • Proteins and fats have no GI rating as they are not altered into glucose. They do reduce the rate of digestion and this lowers the GI rating of meals.

Why is the Glycemic Index Important?

  • Your body performs best when your blood sugar is kept fairly constant.
  • If your blood sugar drops too low, you feel lethargic and experience increased hunger.
  • And if it goes too high, your brain signals your pancreas to secrete more insulin. Insulin brings your blood sugar back down, but primarily by converting the excess sugar to stored fat.
  • When you eat foods that cause a large and rapid glycemic response, you may feel an initial elevation in energy and mood as your blood sugar rises, but this is followed by a cycle of increased fat storage, lethargy, and more hunger!
  • The theory behind the Glycemic Index is simply to minimize insulin-related problems by identifying and avoiding foods that have the greatest effect on your blood sugar.

How Glycemic Load Improves the Glycemic Index

Although most sweets have a relatively high glycemic Index, eating a single amount will result in a relatively small glycemic response because your body’s glycemic response is dependent on both the type and the quantity of carbohydrate consumed. This concept, known as Glycemic Load, was first popularized in 1997 by Dr. Walter Willett and associates at the Harvard School of Public Health. Glycemic Load is calculated this way:

GL = GI/100 x Net Carbs
(Net Carbs are equal to the Total Carbohydrates minus Dietary Fiber) Therefore, you can control your glycemic response by consuming low-GI foods and/or by restricting your intake of carbohydrates.

Limitations of the Glycemic Index and the Glycemic Load

Some proponents of the Glycemic Index would like us to believe that GI and GL are all that matters when selecting which foods to eat. In reality, diet is a more complex issue than that. However, there are also many limitations to GI and GL.

  1. Scarcity of GI data
    Although methods for determining Glycemic Index have been in existence for more than 20 years, GI values have so far only been determined for about 5% of foods.
  2. GI values affected by preparation method
    Generally, any significant food processing, such as grinding or cooking, will elevate GI values for certain foods, because it makes those food quicker and easier to digest. This type of change is even seen with subtle alterations of the preparation, such as boiling pasta for 15 minutes instead of 10.
  3. GI values affected by combination with other foods
    While tests for Glycemic Index are usually done on individual foods, we often consume those foods in combination with other foods. The addition of other foods that contain fiber, protein, or fat will generally reduce the Glycemic Index of the meal.
  4. Individual differences in glycemic response
    The rate at which different people digest carbohydrates also varies, so there are some individual differences in glycemic response between individuals.
  5. Reliance on GI and GL can lead to overconsumption
    It’s important to remember that the Glycemic Index is only a rating of a food’s carbohydrate content. If you use GI and GL values as the sole factor for determining your diet, you can easily end up overconsuming fat and total Calories.

Apples have a GI of 38 (as shown in the table above), and a medium-size apple, weighing 138 grams, contains 16 grams of net carbohydrates and provides a Glycemic Load of 6. This is a low GL, and most would consider the apple to be a very appropriate snack. But now look at peanuts. A 4-oz serving not only weighs less than the apple, but has a much lower GI (14), and provides an even lower GL of 2. Based on Glycemic Load alone, you would have to believe that the peanuts were a better dietary choice than the apple. But if you take a look at the Calories contained in these two foods, you’ll see that the apple contains approximately 72 Calories, while the peanuts contain more than 500! Those 400+ extra Calories are NOT going to help you lose weight.

Mediterranean Diet

  • Diets in Greece, Spain and Italy are associated with healthier and longer life.
  • These diets are rich in fruit, vegetables and fibre. It is high in monunsaturated and polyunsaturated fats and low in saturated fats.
  • Sugary foods are rarely eaten.

Detox Diets

Promoters of detox diets claim improved skin, reduced cellulite, increased energy and a feeling of wellbeing.

  • The theory is that the body needs a boost to remove toxins including  caffeine, alcohol, nicotine and food additives.
  • These diets ban processed food, meat and dairy products, caffeine and alcohol.
  • Organic wholefoods, fruit and vegetables, seeds, nuts, juices and a lot of water drinking are encouraged.
  • These deits are low in calories.
  • They are popular kick-start methods for weight loss.
  • Medically, we believe that the underlying theory is invalid as the body has effective mechanisms for eliminating the toxins in question.

Diuretic Diets

  • Some people feel bloated or puffy and attribute this to fluid retention.
  • These aim to reduce fluid retention.
  • Diuretic diets include watery foods such as citrus fruits, melons, and diuretic herbs such as parsley.
  • Salt in the diet is restricted.
  • These diets are not specifically designed to reduce weight.

Food-Combining Diets

The theory behind these diets is that proteins and carbohydrates cannot be efficiently digested at the same time.

The Hay diet means that no meat pies or meat sandwiches can be eaten and fish and chips are banned.

Fruit must be eaten by itself.

Elements of these diets are consistent with “healthy eating” as they commend plenty of fruit and vegetables.

They are not particularly appetizing and so they are difficult to sustain.

Crash Diets

see Mayo Diet

Food intolerance diets

Many believe that they have an intolerance to certain foods although for the majority of these, there is no objective supporting evidence.

True food intolerance is more likely to result in weight loss than weight gain.

High Fat Diets

Conventionally we believe that low fat in the diet is best suited to weight loss but some promote the opposite.

The theory is that reducing carbohydrates in the diet causes the body to burn its fat stores.

Most dieticians compare these diets to pouring oil on a fire.

Anti-cellulite diets

Cellulite is the colloquial name for lumpy fat that causes the skin to look like orange skin. It particularly accumulates at the thighs and bottom and is more of a problem for women than men. There is no good explanation for cellulite rather than normal fat deposition. Some blame it on toxins or a lymphatic drainage problems. Accordingly, detox diets have been recommended although there is no scientific foundation for this.

Meal Replacement Diets

These reduce energy intake by replacing one or two meals with a low calorie but balanced substitute such as a milkshake or soup etc.

Hypnotherapy to Assist Dieting and Weight Loss

Hypnotherapy may influence the mind to change habits including over eating.

Acupuncture

This form of “healing” has been practised in China for many centuries. Fine needles are inserted in meridians intended to stimulate the body’s natural healing properties.  The objective is to enhance “the balance between the physical, emotional and spiritual harmony” which may have been upset by one of many factors including anxiety and stress.

Prescription Drugs – Xenical – Reductil

These are discussed on Weight-Loss-Dieting

Surgery

  • In the USA more than 100,000 operations are performed each year to assist weight loss whereas in the UK these operations have not become popular.
  • Gastric banding results in a ring at the top of the stomach restricting food intake.
  • Gastroplasty causes the stomach to be partitioned in two. The small segment fills quickly and then empties slowly into the second section.
  • Bypass operations restricts the size of the stomach and bypasses some of the absorbing areas so that fewer calories are absorbed.

Slimming Clubs

The UK slimming clubs have more than a million members with about 90% being women. They offer eating plans and exercise programmes. Many have websites where additional information can be found. Weight gain can be a result of comfort eating related to stress. Everyone is subject to stress but when it becomes difficult to cope with, counselling or psychotharpy can resolve the underlying issues.

Exercise

  • Reducing calorie intake alone can result in weight loss but exercise can help burn calories and may have a significant benefit for those seeking to lose weight. You can also have fun shaping up.
  • Modern life style in developed countries is hostile to people who wish to control their weight. Most of us have sedentary jobs, drive cars instead of walking, use labour saving devices and spend our leisure time watching the TV or going out for meals.
  • The recommended level of exercise to maintain health is 30 minutes of moderate activity each day for at least 5 days each week. Between 30-50% of us fail to undertake this amount of activity.
  • The Chief Medical Officer for England in a report in 2004, concluded that physical inactivity is just as important as smoking and an unhealthy diet in the risk that it poses to health and wellbeing.
  • The report also showed that adults who are physically active have a20-30%  reduced chance of dying prematurely from any cause and are50% less likely to develop heart disease, stroke, diabetes and cancer.
  • Undertaking regular exercise is essential for those who wish to have along and healthy life.
  • A negative balance of 400 calories per day will result in a weight loss of one ounce (of fat) – about 1/2lb each week. Of course, if you start a diet with very little food, your bowel will become less full and this appears to provide a rapid weight loss which of course cannot be sustained.
  • It may be difficult to reduce your calorie intake by 400 calories per day but more realistic to decrease it by 200 calories and increase your exercise by a further 200 calories.
  • Feel good factor.Strengthening the muscles through regular exercise tones them up sop that the body looks trim.
  • It makes you feel uplifted and more confident.

    Table: Activity and Calorie Expenditure

    Activity Calories used in 20 minutes
    Dancing 80
    72 steps / minute 95
    Cycling – flat ground 125
    Golf 100
    Squash 200
    Tennis 140
    Football 140
    Running 190

Boosting Metabolism

  • Exercise tends to replace fat with more muscle and this boosts the body’s metabolism.
  • One pound of fat tissue burns 2 calories each day compared to 35 calories for 1lb of muscle.
  • Thus exercise has an immediate effect on weight loss but a longer term benefit as well.

 

<p “text-align:=”” justify;;=”” margin-top:0cm;=”” margin-bottom:0pt”=””> If you are overweight your fertility will be reduced. This is true for both men and women. It is unclear whether it is the weight that is an independent factor for women or whether other factors such as polycystic ovary syndrome (PCOS -Q7.2) result in both the infertility and excess weight. At the other extreme, if you are under your ideal weight you are more likely to have anovulation problems . The Body Mass Index (BMI) is a ratio used to compare your weight with your height. The BMI is calculated as indicated in Table 9.1.

 

Table 9.1  Calculating your Body Mass Index.

BMI = Weight (Kg) / Height (m)2.

Your BMI should be between 20 and 24. If your BMI is less than 20 you are underweight. You should lose weight if your BMI is between 25 and 29. You are considered to be medically obese if your BMI is 30 or more and you would be regarded as very obese if your BMI is greater than 40.

Table 9.1

Weight Kg and

 

Height in metres and (ft ins)s)

Height (m2) BMI
49

(7st 110lb)

1.63

(5ft 4ins)

1.632 18 (49 / 1.632)
61

(9st 9lb)

1.58

(5ft 2ins)

1.582 24 (61 / 1.582)
90

(14st 2lb)

1.68

(5ft 6ins)

1.682 32 (90 / 1.682)
106

(16st 10lb)

1.5555

(5ft 1ins)

1.552 44 (106 / 1.552)

 

'Stay-at-home' males fueled menopause evolution

‘Stay-at-home’ males sustained menopause development

The evolution of the menopause was ‘kick-started’ by a fluke of nature, but then boosted by the tendency for kids and grandsons to remain living near home, a new research by Liverpool scientists recommends. Menopause is an evolutionary puzzle, as an early end to reproduction seems contrary to the laws of natural choice, where handing down genes to the next generation is the main purpose of life. Yet female human beings, and some other animals, invest up to a 3rd of their lives unable to recreate. Now, for the very first time, researchers from the University of Liverpool and Liverpool John Moores University have utilized a phylogenetic technique to examine the most common evolutionary hypotheses for why females outlive their fertility. One of the most popular explanations advanced for the menopause is the ‘grandma hypothesis’, which suggests that ladies live long previous reproductive age in order to assist effectively raise their grandchildren, therefore enhancing the possibility that their own genes are passed on. Others say that the menopause provides no careful benefit and is an evolutionary fluke or ‘inequality’ which developed due to the fact that human beings were designed for shorter life expectancies but now liv …
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Birth control pill for men actions better

Lead researcher Gunda I. Georg, PhD, of the University of Minnesota College of Drug store, and coworkers recently presented their findings at the 251st National Satisfying & Exposition of the American Chemical Society (ACS) in San Diego, CA. For years, scientists have been striving to establish a contraceptive pill for males. Some research studies have investigated the male hormone testosterone as a possible basis for such a drug; it can trigger infertility at certain doses. “But at those dosages, it does not work for approximately 20 % of men, and it can cause side effects, consisting of weight gain and a decline in ‘good’ cholesterol,” notes Jillian Kyzer, a college student at Minnesota and coauthor of the new research. Other compounds have been examined as a male contraceptive pill, but Georg and her team note there are a number of barriers that need to be gotten rid of before such a drug can reach the market. The pill would need to be soluble – permitting it to be taken orally – and it would need to work fairly rapidly, without impacting a male’s sex drive. What is more, guys would have to be able to utilize the tablet safely for a very long time – even 10 years – and the results on fertility would need to be reversible, with no …
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What will emerging hereditary tools for mitochondrial DNA replacement suggest for clients?

Advanced prenatal techniques, not yet in clinical practice, offer the possible to avoid a harsh multi-system genetic condition passing from mother to kid long previously birth. But these emerging tools raise important questions: might there be unintentional, even permanent dangers to the resulting child– or even that kid’s future descendants? Exist prospective risks to the mom’s health? Exactly what about other prospective effects if its usage is expanded to consist of indicators beyond strict condition avoidance, such as adjusting the tools into conception helps for older women? The tools in question, mitochondrial replacement techniques (MRTs), aim to avoid mother-to-child transmission of mitochondrial DNA condition– a complex set of uncommon disorders caused by defective DNA within the mitochondria, the small energy-producing structures existing outside the nucleus of cells. Such illness may provide at any age or level of seriousness, attacking a combination of organs and systems, frequently fatally. There are no present cures or approved therapies for any of these conditions, which clinicians handle by treating the diverse signs that might gradually impact each patient. Previously this mon.
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For females, a little semen may go a long method

For most individuals in the animal kingdom, sex is a once-and-done occasion. Females from species like rabbits and cows get sperm from their mates and very little else. But in an Online forum post published in Patterns in Ecology & Evolution, scientists suggest that these limited encounters can supply resources to women in influential fluid, and women may have progressed to look for such critical resources, even when the quantity of fluid is small. “Traditionally, the concept is that when this kind of mating takes place, there’s no resource transfer and there’s no paternal care,” states senior author Russell Bonduriansky, an evolutionary ecologist at the University of New South Wales (UNSW). “Males contribute DNA to feed an egg, but our team believe there’s something more intricate going on.” Bonduriansky and his UNSW associates, Angela Crean and Margo Adler, began thinking about evolutionary choices for influential fluid-the liquid part of semen, minus the sperm-in 2014, while studying the offspring of female neriid flies (Telostylinus angusticollis) mated with males of differing sizes. The group discovered that if a male, either huge or small, mated with a female fly before she was fertile, he ‘d pass his sperm alo …
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Absence of stem cells could underlie frequent miscarriage

Miscarriage is the most typical cause of loss throughout pregnancy, impacting 15-25 % of pregnancies. It most frequently takes place at any time within the first 12 weeks of pregnancy. Of women who are attempting to conceive, 1 % will experience frequent pregnancy loss (RPL), or the loss of three or more successive pregnancies. Lots of threat elements have linked to RPL, but researchers have not yet totally understood the underlying causes. Scientists at Warwick University in the UK, led by Jan Brosens, teacher of obstetrics and gynecology, studied tissue samples from the womb lining of 183 ladies. The participants were receiving treatment at the Implantation Research Clinic, University Hospitals Coventry and Warwickshire National Health Service (NHS) Trust in the UK. Cultures from womb biopsies exposed that there was no epigenetic signature showing the existence of stem cells, and there were less stem cells in general in the females who had been through persistent miscarriages, compared to a control group. This lack of stem cells appears to accelerate cellular aging in the womb. Renewal of the womb lining normally accompanies each regular monthly cycle, after each miscarriage and after a successful birth, but it …
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Study shows less invasive hysterectomies helped patients heal and saved money

Research study reveals less intrusive hysterectomies assisted clients recover and conserved cash

A move by The Ottawa Healthcare facility to promote less invasive surgeries for females with serious gynecological issues has accelerated client recovery, resulted in fewer issues and saved the healthcare facility cash, according to a research recently published in the Journal of Obstetrics and Gynaecology Canada. In 2007, The Ottawa Medical facility decided to become a national leader in minimally invasive surgery (MIS), a strategy that uses tiny cuts rather of the huge ones made use of in conventional open surgical treatment. Scientists from The Ottawa Healthcare facility and the University of Ottawa discovered the medical facility’s financial investment in MIS competence and equipment made a big distinction when it concerned hysterectomies, a surgical treatment to get rid of the uterus. Hysterectomies are the most typical surgery for Canadian females after the C-section. In 2012 more than 40,000 ladies had their uterus eliminated, usually due to serious non-cancer conditions like exceedingly heavy periods or unpleasant growths called fibroids. Typically hysterectomies are done through a big cut in the abdomen, and women who undergo this surgery can spend 3 to 4 days in health center and six to 8 weeks recovering. But for MIS hysterectomies, the half-centimeter-long incisions …
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10 Common Labor Problems

We value your privacy Learn more about our commitment to protecting your personal privacy. For complete capability, it is required to enable JavaScript. Here are guidelines ways to enable JavaScript in your web browser. We make use of cookies to personalize your surfing experience. By visiting our website, you consent to their use. Learn more. Usually, the labor and birth process is uncomplicated. However, there are times in which complications develop that may require instant attention. Problems can occur throughout any part of the labor procedure. In this Medical News Today Knowledge Center post, we analyze each of the above 10 issues of labor, including some information on how they can be triggered, treated or avoided. Labor might be described as extended or having cannot advance when it lasts for an abnormally long period of time. For very first time moms, failure to progress is referred to as labor lasting over 20 hours, whereas in moms who have formerly delivered, it is referred to as labor lasting more than 14 hours.4 Extended labor can occur in any phase of labor; nevertheless, it is most concerning during the active phase.4 Discomfort medications can likewise be a contributing aspect by s.
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Intimate partner violence simulation training at MU is initially in country

Intimate partner violence (IPV), has become a common healthcare concern. Instances of attack, battery, rape, stalking and psychological abuse in relationships can be difficult for nurses to handle as they often do not have the suitable training to feel great sufficient to screen patients for IPV. A brand-new training program developed in the Sinclair School of Nursing at the University of Missouri, provides an effective tool to better gear up nurses in helping victims of IPV. The Sinclair School of Nursing is the very first program in the United States to execute such a simulation in their undergraduate curriculum, and the results from the program suggest it could end up being a nationwide model for training nurses. “Almost every nurse will come across a victim of IPV throughout his/her profession,” stated Lea Wood, director of simulation and assistant teaching teacher of nursing. “Yet, numerous service providers feel uneasy when it occurs. They fret that they will say the wrong thing and make the situation even worse for the patient. So while companies understand the importance of screening clients for IPV, the variety of screenings in fact taking place remains low.” Wood’s goal in creating a training program for nursing students was …
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New softer product might reduce issues for ladies suffering from urinary incontinence

Scientists at the University of Sheffield have developed a novel implantable product which could minimize the number of debilitating side-effects that occur as an outcome of utilizing a material that is too stiff for surgical treatment of incontinence. In the UK, it is approximated between 3 and 6 million people suffer with some degree of urinary incontinence. Stress urinary incontinence is the leak of urine when there is pressure on the bladder, such as through sneezing, chuckling or workout, typically as an outcome of giving birth, surgical treatment or menopause. The research study at Sheffield, with two different papers released in PLOS ONE and the Journal of Urology, supplies proof for using a softer and more flexible material to support the urethra. This comes as a brand-new study shows that the long-lasting effect of vaginal giving birth delivery is connected with a virtually twofold increase in the threat of stress urinary incontinence. Current treatment for the condition uses a stiff woven polypropylene mesh gadget, implanted under the urethra to replace harmed or deteriorated tissue. The product utilized in this device was initially designed for hernia repair services but was quickly repurposed in the mid-1990’s for use in uri …
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Major distinctions between male and female bust cancers revealed, but male patients still disadvantaged by lack of research study, say detectives

Male breast cancer (Male BC) has vital biological distinctions that distinguish it from female bust cancer, but to date these have been little studied and Male BC clients have been omitted from lots of scientific trials in breast cancer. Male clients are also usually diagnosed later on when their cancers are advanced, leading to an even worse outcome. New research study has now uncovered a few of the distinctions between the 2 kinds of breast cancer, and the researchers hope that this will help doctors to make better treatment options for Male BC patients. Speaking at the 10th European Bust Cancer Conference (EBCC-10) today (Thursday), Dr Carolien van Deurzen, MD, a pathologist specialising in bust cancer at the Erasmus Medical Centre, Rotterdam, The Netherlands, reported arise from a research of the relationship in between the pathology of different types of Male BC and their diagnosis. The research forms part of the International Male Breast Cancer Program, led by the European Organisation for Research study and Treatment of Cancer (EORTC) in Europe and the Translational Bust Cancer Research study Consortium (TBCRC) in the U.S.A. The group of researchers analyzed 1203 tumour samples from Male BC patie …
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