Authors:
Anderson MC
Institution:
University of Nottingham Medical School, Queen's Medical Centre, UK
Title:
Glandular lesions of the cervix: diagnostic and therapeutic dilemmas (1995-3227).
Source:
Baillieres Clinical Obstetrics and Gynaecology. 9(1):105-19, 1995 Mar
Abstract:
The term 'glandular lesions' applies mainly to the spectrum of intraepithelial neoplasia affecting the glandular epithelium of the cervix, but consideration must also be given to non-neoplastic disorders. Various systems of terminology are used, the most satisfactory being low grade and high grade CIGN. The criteria for histological diagnosis are quite well defined, although the distinctions between low grade and high grade lesions and between intraepithelial and early invasive disease can be problematic. Although many cases are initially diagnosed on smears, the cytological diagnosis can also be difficult, particularly when squamous lesions are also present, as happens in about 50% of cases. Both histologically and cytologically, the differential diagnosis between CIGN and non-neoplastic changes must be made. Treatment for high grade lesions has traditionally been hysterectomy, but there is evidence that conization with careful cytological follow-up may be safe in certain circumstances. Women with low grade lesions are generally managed in the same way; the role of cytological surveillance of women with mild glandular abnormalities in their smear is not clear. Although there is evidence to substantiate the belief that CIGN is a precursor of adenocarcinoma of the cervix, very little is known of the natural history of these lesions, their relations to one another and the significance of the low grade abnormalities. This uncertainty hampers a rational approach to management.
Please click on the required question.
- 1 What is the cervix?
- 2 What is a cervical polyp?
- 3 What is meant by cervical erosion (ectopy) and cervicitis?
- 4 What is the transformation zone?
- 5 What is a 'Paptest' (PAP test (cervical smear) test)
- 6 My PAP smear test (cervical smear) shows inflammation. Should I be worried?
- 7 What are cells and what is an abnormal (pre- malignant) cell?
- 8 My PAP smear test (cervical smear) shows abnormal cells. Does this mean that I have cancer?
- 9 What is meant by the terms pre-malignant cells, dyskaryosis, dysplasia and CIN?
- 10 What are the symptoms of pre-malignancy of the cervix?
- 11 What are benign and malignant tumours?
- 12 Why have I developed a pre-malignant condition of my cervix?
- 13 What is colposcopy?
- 14 What treatments are available for pre-malignant conditions of the cervix?
- 15 Can pre-malignant conditions of the cervix be cured?
- 16 How can I be re-assured that the pre-malignant changes will not recur?
- 17 How can we prevent carcinoma of the cervix?
- 18 Is there a reason to screen for HPV?
- 19 Support Groups.
- 20 Are there any support groups?
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