Acta Obstet Gynecol Scand. 1996 Feb;75(2):139-43.
Pregnancy outcome after laser surgery for cervical intraepithelial neoplasia.
Authors:
Forsmo S , Hansen MH , Jacobsen BK , Oian P .
Institute of Community Medicine, University of Tromso, Norway.
Background:
Little is published about obstetrical problems after treatment of cervical intraepithelial neoplasia with the C02-laser. The aim of this study was to determine the risk of low birth weight in the subsequent pregnancy after laser conization or vaporization in a follow-up study of women treated for cervical intraepithelial neoplasia (CIN). Methods. Of 319 women treated for CIN with the C02-laser in the Department of Obstetrics and Gynecology, University Hospital of Tromso, Norway and followed for pregnancy outcome, 87 women had given birth (after 24th week) four to nine years after treatment. Sixty-five women had undergone conization and 22 women had been treated with vaporization. For each delivery, two controls matched for parity, age (+/- 3 years) and place of delivery were identified. The material was analyzed as a matched cohort study.
Results:
A strong relationship was found between conization and low birth weight. Mean birth weight after conization was 3185 g vs 3473 g, in the control women (p=0.03). Thirteen (20%) infants from women subject to conization had birth weight less than 2500 g. Relative risk of birth weight<2500 g was 2.2 (1.04-4.5) after conization, for<2000 g and< 1500 g the risk was 3.5 (1.02-12.0) and 10.0 (1.2-85.6), respectively. Four women (6.2%) with normal deliveries prior to conization experienced one or several stillbirths after treatment. No difference in birth weight was observed for women after vaporization compared to their controls.
Conclusion:
Excisional surgery on the cervix increases the risk for low birth weight in subsequent pregnancies. Pregnant women with prior conization need careful antenatal care.
Please click on the required question.
- 1 What is the cervix?
- 2 What is a cervical polyp?
- 3 What is meant by cervical erosion (ectopy) and cervicitis?
- 4 What is the transformation zone?
- 5 What is a 'Paptest' (PAP test (cervical smear) test)
- 6 My PAP smear test (cervical smear) shows inflammation. Should I be worried?
- 7 What are cells and what is an abnormal (pre- malignant) cell?
- 8 My PAP smear test (cervical smear) shows abnormal cells. Does this mean that I have cancer?
- 9 What is meant by the terms pre-malignant cells, dyskaryosis, dysplasia and CIN?
- 10 What are the symptoms of pre-malignancy of the cervix?
- 11 What are benign and malignant tumours?
- 12 Why have I developed a pre-malignant condition of my cervix?
- 13 What is colposcopy?
- 14 What treatments are available for pre-malignant conditions of the cervix?
- 15 Can pre-malignant conditions of the cervix be cured?
- 16 How can I be re-assured that the pre-malignant changes will not recur?
- 17 How can we prevent carcinoma of the cervix?
- 18 Is there a reason to screen for HPV?
- 19 Support Groups.
- 20 Are there any support groups?
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