Monitoring the woman with
pre-eclampsia / eclampsia. |
The blood pressure should be checked each 15 minutes until the woman is
stabilised and then every 30
minutes in the initial phase of assessment.
The blood pressure should be
checked 4-hourly if a
conservative management plan is in place and the woman is stable and
asymptomatic.
Assessment of the woman requires a full blood count, liver function and
renal function tests. These
should be repeated at least daily when the results are normal but more
often if the clinical condition
changes or if there are abnormalities.
Clotting studies are not required if the platelet count is over 100 x
106/l.
Close fluid balance with charting of input and output is essential. A
catheter with an hourly urometer is
advisable in the acute situation, especially in the immediate postpartum
period.
In pre-eclampsia, there can be a rise in uric acid that correlates with
poorer outcome for both mother and baby.9902
This rise confirms the diagnosis of pre-eclampsia and confers an
increased risk to the mother and baby but the
levels,in themselves, should not be used for clinical decision-making.
Renal function is generally maintained in pre-eclampsia
until the late stage unless HELLP syndrome develops.8201,
9903If creatinine
is found to be elevated early in the
disease process, underlying renal disease should be suspected. In severe
disease, serum creatinine can be seen to
rise and is associated with a worsening outcome9903
but renal failure is
now uncommon in pre-eclampsia in the
developed world and when it does occur it is usually associated with
haemorrhage, HELLP syndrome or sepsis.
A falling platelet count is associated with worsening disease and is
itself a risk to the mother.7801
However, it is
not until the count is less than 100 x 106/l that there may be an
associated coagulation abnormality.9904
Other
parameters, such as platelet volume, may be of benefit but are as yet
unproven. A platelet count of less
than 100 should be a consideration for delivery. An AST level of above
75 iu/l is seen as significant and a
level above 150 iu/l is associated with increased morbidity to the
mother. A diagnosis of HELLP syndrome
needs confirmation of haemolysis, either by LDH levels, as commonly
assessed in the USA, or by blood film
to look for fragmented red cells. An AST or ALT level of above 70 iu/l
is seen as significant and a level
above 150 iu/l is associated with increased morbidity to the mother.13
The platelet count would have to be
below 100 x 106 to support the diagnosis.