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The Effectiveness Of
Antenatal Corticosteroid Therapy
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Br J Obstet Gynaecol. 1999 Sep;106(9):977-9.
Are we prescribing multiple courses of antenatal corticosteroids? A
survey of practice in the UK.
Brocklehurst P, Gates S, McKenzie-McHarg K, Alfirevic Z, Chamberlain G.
National Perinatal Epidemiology Unit, Radcliffe Infirmary, Oxford, UK.
A postal questionnaire concerned with prescribing antenatal
corticosteroids was sent to one named clinician at each of 279 obstetric
units in the UK. They were asked whether their unit prescribed repeated
courses, the indications for which these would be prescribed, the
interval between courses, the drugs and regimens used and whether they
would be willing to participate in a proposed randomised controlled
trial. The response rate was 75%. Of the respondents, 98% prescribed
repeated courses; the indications most commonly cited by units who
prescribed steroids were prelabour spontaneous rupture of membranes
(84.2%) and suspected preterm labour (81.8%). 70.6% of units were
willing to participate in the proposed trial.