Bid to ease burden of heavy periods steps up with new UK drug trial

Bid to alleviate problem of heavy periods steps up with brand-new UK drug trial

Females who suffer heavy durations are being invited to join a research study to test a new treatment for their condition. The trial will discover if increasing levels of a hormonal agent produced in the lining of the womb can decrease blood loss throughout menstruation and ease females’s signs. Scientists think that a hormone – called cortisol – assists the small capillary in the womb lining to work well. If cortisol levels are too low in the womb, it can enhance blood loss, scientists state. This study will check whether a drug that mimics the actions of cortisol – called dexamethasone – will improve the hormonal agent to normal levels and decrease menstrual blood loss. The research aims to identify whether a brief course of the drug, at a low dose, could also be utilized to handle heavy durations. Ladies who join the research study will be asked to monitor their durations for 2 months. They will then be randomly assigned to receive either a short course of dexamethasone or a placebo tablet for 5 days prior to their period is due, for the following three months. As is usual in clinical trials, neither the doctors nor the individuals will understand which medication they receive. Professor Hilary Critchley of the Univers …
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HPV: cervical peeling as a treatment for precancerous conditions

Scientists at the Comprehensive Cancer Center (CCC) of MedUni Vienna and Vienna General Hospital have developed a brand-new treatment for the pre-stages of cervical cancer, caused by human papilloma virus (HPV) infection. The treatment includes using 85 % trichloroacetic acid, an acid that is generally used for medical and cosmetic skin peeling. The scientists revealed that complete remission was accomplished in 82 % of the patients after only one application. Furthermore, the new treatment is extremely simple for specialists to use and is extremely cost-effective. The study was released in Obstetrics & Gynecology, the official publication of the American Society of Obstetrics and Gynecology. The conventional treatment for serious pre-stages of cervical cancer consists of a surgery, so-called cervical conization. It’s major side-effect is a marked increase in the rate of early births. The present research study shows that it is possible to extra clients the difficult operation and the increased risk of delivering prematurely: by utilizing a gentle and comparatively basic treatment, where 85 % trichloroacetic acid is dabbed onto the affected location of the cervix. Since fairly focused acid is utilized …
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Endometriosis might raise females’s heart problem threat

The research was led by Fan Mu, who was a research assistant at Brigham and Women’s Hospital and Harvard Medical School in Boston, MA, at the time of research study. Endometriosis is a condition in which the tissue that typically lines the uterus grows on the exterior of the reproductive organ or other areas of the body, including the ovaries and the fallopian tubes. In the US, it is estimated that a minimum of 11 % of females – or 6 million – aged 15-44 have endometriosis, with the condition most common among those in their 30s and 40s. While unpleasant menstrual cramps can be an indication of endometriosis, lots of girls and ladies are unaware of this, indicating the condition typically goes undiagnosed. Mu and associates set out to examine whether females with endometriosis are at higher risk for cardiovascular disease – the leading cause of death for both males and females in the US. The group assessed the health records of 116,430 women who were part of the Nurses’ Health Study II. Through medical assessment, endometriosis was diagnosed in 11,903 women over Twenty Years of follow-up. The researchers discovered that females with endometriosis were 1.91 times most likely to establish chest pain, or angina, 1.52 times more likely to have …
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Pitt finding suggests new cardiovascular disease screening target for middle-aged black women

Middle-aged black women have greater levels of a protein in their blood related to a predictor of heart problem than their white equivalents, even after other factors, such as obesity, are taken into consideration, according to a study conducted by the University of Pittsburgh Graduate School of Public Health and School of Medicine. The finding, reported today in the journal Menopause, suggests routine blood testing of black menopausal females may be warranted to identify their cardiovascular disease threat and possibly when to start therapies, such as aspirin and statins. The research study was moneyed by the National Institutes of Health (NIH). “Numerous previous researches have revealed that black ladies are at greater danger for heart disease than white females; however, standards for examining heart disease risk in asymptomatic grownups do not suggest selective race- or ethnic-based risk-assessment,” said lead author Norman C. Wang, M.D., M.S., assistant teacher in Pitt’s School of Medicine. “Our study exposed for the very first time that in black, but not white, women going through menopause, greater levels of a quickly determined risk factor for cardiovascular disease are related to greater amoun …
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Narcissism connected to sexual assault perpetration in college, research study discovers

Nearly 20 percent of college males have dedicated some sort of sexual attack, and 4 percent have committed rape, according to a research study published by University of Georgia researchers who were examining the link between different kinds of narcissism and the perpetration of sexual attacks. The research study discovered a strong connection in between pathological narcissism and sexual assault perpetration through a study of 234 male university students, mostly in their very first and 2nd years of college. Its findings related to perpetration rates were mostly constant with previous researches, stated the research study’s lead author Emily Mouilso, a scientific assistant professor in the Franklin College of Arts and Sciences’ psychology department. Individuals who show attributes of pathological narcissism have difficulties when it concerns connecting to others, Mouilso discussed. Non-pathological narcissism, on the other hand, can be rather helpful since it materializes in high self-esteem and makes it much easier for individuals to get rid of failures, research study co-author Karen Calhoun stated, explaining that it’s what some scientists call the “healthy” type of narcissism. “As we forecasted, the elements of narcissism that we believed would be related were (related)– the lack of empathy, the entitlement elements of narcissism,” Mouilso said. What shocked them was the link between susceptible narcissism and rape perpetration. Vulnerable narcissists express high levels of self-esteem but are actually really insecure, Mouilso said. The study discovered that males with vulnerable egotistical characteristics were more likely to utilize alcohol or other date-rape drugs to cripple their victims, a finding that is especially concerning on a college school, Mouilso stated. “I think people don’t realize how widespread drinking is” in colleges, stated Calhoun, a teacher emerita in the psychology department. “It’s not a lot just how much they drink overall for females that makes them vulnerable; it’s how much they drink at a time, the binge drinking, the getting drunk and simply not being alert and aware of their environments or the threats included. That actually puts ladies at danger.” Mouilso and Calhoun explained their results in the context of the theory that there are two general paths that frequently lead to perpetration. “If completion item is perpetration, there’s more than one type of profile that would make you most likely to perpetrate a sexual assault,” Mouilso stated. “One of those streams is promiscuity– so individuals who have greater levels of sexual interest and more regular sexual partners, they’re more OK with impersonal sex. That’s one stream of risk aspects. “The 2nd course is the hostile masculinity path. That has more to do with how you look at ladies, so having a hostile and mad orientation toward females in general and thinking that relationships are adversarial … it’s more about, what can I leave this individual that I desire? I don’t really care all that much about what they desire.” She discussed that people can be high or low on factors in both of those tracks, but if a person has both of them together, it makes that person a lot more most likely to perpetrate a sexual assault, according to existing theory. Narcissists feel a sense of entitlement to anything they want, something that makes it easier for them to justify their aggressive and often illegal habits, Mouilso stated. Many previous studies have used incarcerated sex culprits as their sample swimming pool, which makes it more difficult to generalize lead to other populations. Mouilso and Calhoun’s sample of college males is fairly representative of big Southeastern university male populations. Frequently the view of college males tends to be an old-fashioned, “children will be boys” attitude when it pertains to acts of sexual hostility, Mouilso stayed. “I simply do not think that that’s precise,” Mouilso said, “so this research helps to shed light on some of the commonalities in the character profile in between men who wind up in jail and men who are walking because they have not been captured.” The idea that many sexual assault perpetrators are strangers who grab ladies in dark alleys isn’t precise, Mouilso stated. “It’s less most likely to be a complete stranger who jumps from the bush,” she said. “It’s most likely to be somebody you know like the guy sitting next to you in your intro psych class.” The social belief in “unfamiliar person risk” puts people at threat since they are looking for the psychopathic person on the corner rather than at the individuals in their lives who have much greater access and opportunity to perpetrate, the scientists stated. Researches of non-incarcerated criminals work in establishing prevention programs that could give ladies a more accurate idea of what to watch out for. Although the percentage of college guys who dedicated sexual attacks is disturbing, the findings suggest that it’s a “small portion of men who are doing the majority of” the assaults, something that gives the researchers hope, Calhoun stated. “If we might recognize them and intervene in some method, that would provide you some better hope of avoiding it,” she said.See all stories on this subject

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