Ovary function restored in infertile mice using 3-D-printed scaffolds

Ovary function restored in sterile mice using 3-D-printed scaffolds

The research, released in Nature Communications, is the work of a team that includes members from the Northwestern University Feinberg School of Medicine in Chicago and Northwestern’s McCormick School of Engineering in Evanston, both in Illinois. Healthy ovaries are not only essential for fertility; they likewise produce hormonal agents that set off adolescence and menopause. The scientists undertook the study because they wish to find a way to assist clients of all ages who undergo treatments (such as for cancer) that hinder their ovary function. Young patients who lose ovary function often require hormone replacement treatment to trigger puberty. In their study paper, the authors keep in mind that current methods – including in vitro fertilization (IVF) and ovarian transplants – do not offer “long-lasting services and leave pediatric patients with metastatic disease without options.” There have been numerous attempts to engineer ovaries using a series of biomaterials combined with hair follicles – the spherical pockets inside ovaries that contain immature egg cells and produce hormones – but these have had limited success. The authors discuss that a person of the obstacles to tissue engineering a replacement ovar …
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