The transfer of chromosomally 'abnormal' embryos can still result in pregnancy in IVF

The transfer of chromosomally ‘abnormal’ embryos can still lead to pregnancy in IVF

IVF embryos whose cells have mixed chromosomal profiles – one typical, another abnormal – still have the possible to implant in the uterus and become a healthy pregnancy, according to a research study provided today at the 33rd Annual Satisfying of ESHRE. This pattern of embryonic mosaicism, which is characterised by the presence of 2 or more genetically unique cell lineages, generally one with a chromosome problem and the other with a normal chromosome structure, has ended up being a controversial topic in recent months, with debate over their prospective practicality. In the light of this newest research study, which was carried out by the GENOMA group and European Medical facility IVF Center in Rome, Dr Francesco Fiorentino from the Molecular Genes Lab of GENOMA, who will provide today’s study, stated that its results “validate that mosaic embryos can develop into healthy euploid [chromosomally healthy] babies”. This possibility was very first raised by Dr Fiorentino’s group and the European Hospital in a letter to the New England Journal of Medicine in November 2015, which explained six healthy shipments in a small series of 18 women for whom embryo screening had discovered no chromosomally normal (euploid) e.
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